Your benefit: A step ahead with our know how and customized services
- Accelerate your drug development by a ensuring fast, comprehensive GLP graded viral safety testing package
- Decrease your risk of a false positive by applying the PathoQuest viral safety NGS transcriptome approach
- De-risk your drug development pipeline using a broad-range, powerful safety test
Metagenomics NGS Services offered by PathoQuest are fast, cost-effective and fully integrated. High Throughput Sequencing services are dedicated to genetic characterization and viral safety testing allowing you to do one test instead of multiple assays.
Our non-targeted approach enables the detection of a broad range of viruses
- No need for specific amplification (cell culture, in vivo…)
- Capacity to detect new viral variants
- Upfront sample preparation may be adapted to many matrix including cell banks, virus stocks, raw materials and product intermediates
- Avoid development of specific neutralizing antibody (no antiserum from animal origin)
- Turnaround time < 3 days (Emergency test)
- Our proprietary sample preparation process enables the detection of adventitious virus in highly concentrated vaccinal viral seed stocks and bulk harvest
- Enables detection of RNA and DNA viruses (2 tests)
Genomic Testing for Biologics
Our non-targeted approach enables the detection of a broad range of viruses
- Using a transcritomic (RNASeq) NGS approach at the preMCB level ensures the highest safety level and de-risks the drug development process
- Our trancriptomic NGS approach detects only replicative viruses and reduces the risk of false positives (dead viral sequences, wrong taxonomic assignation, etc.)
- The high precision (accuracy) of Illumina sequencing enables precise genome analysis to document purity and the clonality of cell lines
Genomic Testing for Gene & Cell Therapy
Our non-targeted approach enables the detection of a broad range of viruses
- Using a transcritomic (RNASeq) NGS approach at the preMCB level ensures the highest safety level and de-risks the drug development process
- Our trancriptomic NGS approach detects only replicative viruses and reduces the risk of false positives (dead viral sequences, wrong taxonomic assignation, etc.)
- The high precision (accuracy) of Illumina sequencing enable precise genome analysis to document the vector and insertion sites sequence in the modified cells